How does protein affect insulin dosing for meals?

According to a new study that was published in Diabetic Medicine, people with Type 1 diabetes need almost 50% more insulin to keep their glucose levels stable after a high-protein meal.

 

Researchers found that most of the extra insulin was needed in the two hours following the meal. However, there was a lot of variation between the extra insulin needed by different people in the study.

 

This is the first study to look at insulin needs of a high-protein meal vs a low-protein meal. In the study, the carbs and fat content are kept exactly the same in each meal.

 

Why the research took place:

People living with Type 1 diabetes are currently encouraged to adjust their insulin levels depending on the carb content of their meal. However, recent evidence suggests that fat and protein can also affect glucose levels. Therefore they should also be taken into account when an individual is calculating their insulin dosage.

 

The Research:

11 teenagers took part in the study. Each person ate pasta meals that contains 30g of carbs, 8g of fat and either 60g or 5g of protein.

 

Researchers looked at how much insulin a person needed and when they needed it, in order to keep their blood glucose levels stable at around 5.5mmol/l both during and after meals.

 

The findings:

Those that were eating the high-protein meal needed, on average, 54% or 3.6 additional units of insulin compared to those eating the low-protein meal.

 

However, the insulin needs varied greatly between the participants eating the high-protein meal. This ranged from 1.3 units less than the low-protein meal up to 9.4 additional units.

 

What does this mean?

The results suggest that carbs are not the only food group that affects glucose levels and insulin needs. However, this was a small study with a small sample size. Therefore, further testing is needed to better understand how protein affects insulin dosing.

“Given that this is the first study to suggest this early increase in insulin requirements, further research is required before the development of definitive recommendations around the optimal timing of insulin delivery to manage high-protein meals.”


  • Research news

    First Ever Person with Type 1 Diabetes Receives Experimental Encapsulated Human Stem Cell-Derived Beta Cell Replacement Therapy. Diabetes Ireland Research Alliance, a subsidiary of Diabetes Ireland, and a partner of JDRF (UK) is delighted to hear of this milestone. Encapsulated cell therapies have the potential to fundamentally transform the lives of people with type 1 diabetes.

    Read More
  • Managing my Type 2 Diabetes – Public Education Meeting

    As more and more people are being diagnosed with diabetes, HSE services are being simply overwhelmed and are struggling to cope with the number of patients seeking diabetes treatment. Meanwhile, people with diabetes have to manage their condition on a day to day basis. Without proper education and understanding of the condition, this is not easy.

    Read More
  • The National Diabetes Cup 2014 scoops award

    It's official, The National Diabetes Cup 2014 was award winning. The National Diabetes Cup was recently nominated for an IMSTA’s Med Tech Award for Community And Social Awareness and was beat out some stiff competition to be chosen as the winner. As massive well done to Bayer and Medtronic, our sponsors. But a special thank you to everyone who took part and help make the event such a success.

    Read More
  • Giant Breakthrough in Type 1 Diabetes Research

    Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes.

    Read More
  • National Fitness Day 2014

    Ireland’s National Fitness Day has been set up to encourage people to become more active. This initiative has been  established by Energie Fitness Clubs and we are delighted to be... View Article

    Read More